Search on: RAF MAP KINASE KINASE KINASES 
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Descriptor English:   raf Kinases 
Descriptor Spanish:   Quinasas raf 
Descriptor Portuguese:   Quinases raf 
Synonyms English:   Kinases, mil-raf Protein
Kinases, raf
MIL RAF Proteins
MIL-RAF Proteins
Protein Kinases, mil-raf
Proteins raf, Proto-Oncogene
Proto Oncogene Proteins raf
Proto-Oncogene Proteins raf
Proto-Oncogene Proteins, raf
mil raf Protein Kinases
mil-raf Protein Kinases
raf MAP Kinase Kinase Kinases
raf Proto Oncogene Proteins
raf Proto-Oncogene Proteins
raf Serine Theonine Protein Kinases
raf Serine-Theonine Protein Kinases  
Tree Number:   D08.811.913.696.620.682.700.559.842
D12.644.360.400.842
D12.776.476.400.842
D12.776.624.664.700.204
Definition English:   A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION. 
History Note English:   2005 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38718 
Unique Identifier:   D048490 

Occurrence in VHL: 		 

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